Enzyme Discovery Platform for Industrial Biocatalysis: The MetXtra™ Technology

Production of specialized, highly efficient enzymes

Traditional enzyme discovery approaches often fail to explore the vast diversity of natural sequence space, limiting innovation in biocatalysis. The MetXtra™ platform was developed to overcome these limitations by integrating multiple advanced technologies into a single discovery workflow.

Industrial biocatalysis offers highly efficient and selective solutions for chemical and pharmaceutical processes. However, one of the key challenges remains: identifying enzymes that perform reliably under real industrial conditions.

With the MetXtra™ technology platform, we address this challenge by integrating multiple advanced technologies into a single discovery workflow.

The MetXtra™ Platform: Expanding Enzyme Discovery Beyond Natural Limits

  • MetXtra™ combines natural diversity with state-of-the-art bioinformatics and artificial intelligence to provide superior enzymes with high efficacy.
     
  • Unique enzymes can be identified in BRAIN Biotech’s proprietary database of unexplored, Nagoya-compliant, novel sequences resulting from the fusion of the metagenomic sequence databases of BRAIN Biotech AG and Biocatalysts Ltd.
     
  • The discovery of enzymes is tailored to the desired application utilizing BRAIN Biotech´s broad sequence and structural bioinformatics and AI toolbox. Additionally, new enzymes outside the natural sequence space are designed via artificial intelligence.

MetXtra gives our customers access to a comprehensive database of previously undiscovered enzymes. The cutting-edge bioinformatics methods allow us to quickly and precisely identify the appropriate enzyme for their specific applications, giving them a significant competitive advantage.

Dr. Alexander Pelzer - VP, Head of Research and Development at BRAIN Biotech Zwingenberg

End-to-end: From Enzyme Discovery to Industrial Application

BRAIN Biotech offers customers access to the MetXtra™ technology platform if they want to establish and optimize biocatalytic processes, develop novel enzyme solutions and generate IP or FTO.

A key advantage of the MetXtra™ platform is its integration into a broader development pipeline. Beyond discovery, BRAIN Biotech supports:

  • enzyme optimization and engineering
  • development of microbial production strains
  • scalable process development and industrial implementation

This enables a seamless transition from discovery to production, allowing companies to implement new enzyme solutions more efficiently.

Develop Novel Enzyme Solutions for Your Application

Whether you are exploring new biocatalytic pathways or optimizing existing processes, BRAIN Biotech supports you from enzyme discovery to industrial implementation.

 Request a consultation

 

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