a collage of probiotic strains

Meet our microbes

Our appeal: more spore formers in the world of (human) probiotics! As supplements and even baby food, they already have a long tradition in Asia. In farm animals, they are the probiotic of choice. But there are many more ways to put them to good use, taking advantage of their evolutionary diversity and pursuing new approaches.

From the large microbial diversity in the BRAIN Bioarchive, two bacterial genera in particular are worth highlighting in connection with probiotics: Lactobacillus and Bacillus. Both have been traditionally used in food production for centuries. In probiotics for humans, representatives of Lactobacillus are mostly used. However, there is more and more evidence that Bacillus not only has its own life cycle in the gastrointestinal tract, but also makes a significant contribution to human health.

As your partner in product development we offer a proprietary selected collection of

Spore-forming bacteria

200 proprietary strains from diverse habitats (e.g. animal gut, vegetables, traditional fermented food, plant symbionts, soil)

Lactic acid bacteria

100+ proprietary strains e.g. from (plant-based) traditional fermented foods

Our strains are pre-characterized in terms of safety and performance

  • genome sequence closed, annotated, plasmid check
  • antimicrobial resistance (AMR) checked according to EFSA
  • cytotoxicity checked according to EFSA
  • in silico identification of target enzymes (secretome)
  • in silico identification of benefical metabolites (metabolome)
  • for spore candidates: producibility and heat stability

Our superheroes

Spore-forming bacteria are true heroes when it comes to stability and versatility

Bacteria of the genus Bacillus are able to defy the harshest conditions. To do so, they resort to their ultimate means of survival: the metabolically inactive spore, a natural form of survival. With it, Bacillus bacteria not only outlast time (e.g. hundreds of years in the soil), but also literally travel across the planet, as they are notorious for surviving on the outside of orbiting space stations, for example.

Travel has also shaped their ability to adapt to and thrive in a wide variety of habitats, such as vegetable roots, rice paddies, sea grass, and the intestines of humans and animals.

So versatile, they can …

  • help with immune modulation (anti-inflammation, GALT development)
  • promote digestibility (enzymes)
  • maintain the integrity of the intestinal barrier
  • alleviate irritable bowel syndrome
  • help fight against colonization with pathogens (resilience e.g. against Staphylococcus aureus)
  • help to keep farm animals healthy (less use of antibiotics)
  • help promote and protect the growth of plants (e.g. vegetables)
  • help to clean surfaces in the household
  • repair cracks in cement

Lactic acid bacteria are true heroes at living inside us, communicating with us and supporting our health

Members of the genus Lactobacillus have a clear preference for nutrient-rich habitats. Although they are found in numerous environments (e.g. silage, vegetables), they are best known to us as dairy cultures and inhabitants of our bodies. Commensal Lactobacilli include a wide variety of species that specialize according to age and body region. They support us with nutrients such as B vitamins and we are in direct communication with them by means of special receptors (e.g. in our intestines).

So supportive, they can help with

  • Inflammation
  • Diarrhea
  • Metabolic health (cholesterol)
  • Oral health
  • Skin health
  • Urogenital health

BRAIN Biotech as your partner in product development

If you want to expand your probiotic product pipeline to differentiate your range, or if you don't have any strains yet but want to enter the probiotic market – BRAIN Biotech AG is your partner of choice for product development. We can identify, select, characterize, improve and develop probiotic strains for various target applications.

Learn more about our offers regarding probiotics

Probiotic strains

Probiotics – mighty little helpers at your service

To overview

a scientist in the fermentation lab

Our technology portfolio to address pro-/ post-/ pre- and synbiotics

To our probiotic technology portfolio

Innovative new products with probiotics

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