Press releases
2 February 2022, Potsdam

AnalytiCon Discovery and Pharvaris extend their collaboration

AnalytiCon Discovery, a first-class provider of natural product, drug discovery and development services, today announced the extension of their research and development collaboration with Pharvaris, a clinical-stage company focused on bringing oral bradykinin-B2-receptor antagonist small molecules to patients.

AnalytiCon Discovery, a leader in the design and development of chiral compound libraries, has earned a strong reputation over the years as a drug discovery CRO in a wide range of collaborations. A key success story comes from its partnership with Pharvaris, a clinical-stage company specializing in the development of bradykinin-B2-receptor antagonists for the treatment of hereditary angioedema (HAE) and other bradykinin-B2-receptor-mediated indications.

Pharvaris has initiated Phase 2 studies of a bradykinin-B2-receptor antagonist for both on-demand and prophylactic treatment of HAE. With the extension of this collaboration for an additional 18 months, AnalytiCon Discovery and Pharvaris will continue to work together on the research and development of new bradykinin-B2-receptor antagonists to treat HAE and other conditions.

Jochen Knolle, Ph.D., chief scientific officer of Pharvaris, states: “We are thrilled that our collaboration with AnalytiCon Discovery has been extended. They have been our research partner from Pharvaris‘ inception and will continue to be instrumental in our drug discovery efforts on the development of new bradykinin-B2-receptor antagonists with the potential to treat additional indications.”

Christoph Gibson, Vice President Drug Discovery and Development at AnalytiCon Discovery, says: "We are pleased to extend our fruitful collaboration with Pharvaris focussing on the characterization and development of new bradykinin-B2-receptor antagonists. This will open up new therapeutic indications for this highly attractive drug target."

Lutz Müller-Kuhrt, chief executive officer of AnalytiCon Discovery, adds: "The collaboration between AnalytiCon Discovery and Pharvaris is an excellent example of a synergistic partnership between early-stage drug discovery and development experts to advance therapies efficiently in clinical development.”

Über AnalytiCon

AnalytiCon Discovery provides drug discovery and development services. The technology platform builds on an extensive reservoir of synthetic and natural compounds and is complemented by a first-class drug discovery and development team. AnalytiCon’s expertise also includes the identifica-tion and development of novel ingredients for the cosmetic and food industries. AnalytiCon has been a member of the BRAIN Group since 2013. Further information: www.ac-discovery.com

Contact

AnalytiCon Discovery GmbH
Dr. Lars Ole Haustedt
Vice President / Projects and Innovation
Phone: +49 175 560 2427
Email: l.haustedt@ac-discovery.com

AnalytiCon Discovery, LLC (USA)
Dr. Dietmar Wolf
Chief Business Officer
Phone: +1 240654 7575
Email: d.wolf@ac-discovery.com



About BRAIN

BRAIN Biotech AG is a leading European supplier of bio-based products and solutions such as enzymes and proteins, microbial production strains, natural compounds and biotechnological solutions for more sustainable industrial processes. The company focuses on the fields of nutrition, health and environment.

BRAIN Biotech AG is the parent company of the international BRAIN Biotech Group. The Group's business activities are divided into three segments: The BioProducts segment comprises the product business with specialty enzymes and other proteins, for which the Group operates fermentation facilities in the United Kingdom and production facilities in continental Europe and the United States. The BioScience segment offers research-intensive custom solutions based on enzyme technology, strain development, bioprocess development and natural product screening. The BioIncubator segment conducts its own R&D projects or those initiated with partners with high value-added potential. A particularly promising incubator project is the development of the Company's own CRISPR-based gene editing technology platform, which is currently being established and expanded by Akribion Genomics (in foundation planning).

Through its own R&D activities, BRAIN Biotech Group is continuously expanding its product portfolio in the field of specialty enzymes and small molecules. The latter are the starting point for screenings, e.g. for novel drug candidates for pharmaceutical applications.

BRAIN Biotech AG has been listed on the Prime Standard of the Frankfurt Stock Exchange since February 9, 2016 (ticker symbol: BNN; securities identification number: ISIN DE0005203947 / WKN 520394). The company employs approximately 330 people and generated revenues of EUR 55,3 million in the fiscal year 2022/23.

For more information, please visit: https://www.brain-biotech.com, LinkedIn, Threads and YouTube.

Disclaimer

This press release contains forward-looking statements. These statements reflect the current views, expectations, and assumptions of the management of BRAIN Biotech AG, and are based on information currently available to the management. Forward-looking statements are no guarantees of future performance, and entail both known and unknown risks as well as uncertainties that could cause actual results, performance or events to differ materially from those expressed or implied in such statements. Numerous factors exist that could influence the future performance of and future developments at BRAIN Biotech AG and the BRAIN Biotech Group. Such factors include, but are not limited to, changes in the general economic and competitive environment, risks associated with capital markets, currency exchange rate fluctuations, changes in international and national laws and regulations, in particular with respect to tax laws and regulations, as well as other factors. BRAIN Biotech AG does not undertake any obligation to update or revise any forward-looking statements.

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